o:8611 Review of antimicrobial-resistant ESKAPEE pathogens in food sources and their relevance to the One Health approach en Antimicrobial resistance (AMR) is a growing concern globally, particularly with ESKAPEE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, Enterobacter spp., and Escherichia coli) which have developed multidrug resistance. While traditionally associated with health- care settings, these pathogens are increasingly being found in food sources, particularly meat products, and agricultural environments. This review explores the mechanisms by which ESKAPEE pathogens acquire antimicrobial resistance, their occurrence in meat and other food products, and the implications for food safety. It also discusses the environmental res- ervoirs, including water sources, and the challenges posed by the spread of these pathogens within the meat production and processing chains. Surveillance programs monitoring the prevalence of AMR in the food industry, especially in relation to meat, are outlined, high- lighting the need for improved detection and control measures. The review emphasizes the importance of a One Health approach, recognizing the interconnectedness of human, animal, and environmental health. Addressing AMR in meat and food production requires coordinated efforts across sectors, including public awareness campaigns and enhanced food safety proto- cols, to limit the spread of resistant ESKAPEE strains. Antimicrobial resistance ESKAPEE pathogens, Meat safety, Foodborne pathogens, One Health, Multidrug resistance 1552099 10.18485/meattech.2025.66.3.48 2025-12-05T08:55:41.855Z 44 yes 46 Dunja Mišić Institute of Meat Hygiene and Technology, Kaćanskog 13, 11000 Belgrade, Serbia Review of antimicrobial-resistant ESKAPEE pathogens in food sources and their relevance to the One Health approach https://orcid.org/0009-0006-2213-2612 Vesna Đorđević Institute of Meat Hygiene and Technology, Kaćanskog 13, 11000 Belgrade, Serbia Review of antimicrobial-resistant ESKAPEE pathogens in food sources and their relevance to the One Health approach person https://orcid.org/0009-0008-5187-4089 Vesna V. Janković Institute of Meat Hygiene and Technology, Kaćanskog 13, 11000 Belgrade, Serbia Review of antimicrobial-resistant ESKAPEE pathogens in food sources and their relevance to the One Health approach person https://orcid.org/0009-0003-0095-1498 Branko Velebit Institute of Meat Hygiene and Technology, Kaćanskog 13, 11000 Belgrade, Serbia Review of antimicrobial-resistant ESKAPEE pathogens in food sources and their relevance to the One Health approach person https://orcid.org/0000-0002-7577-8074 Radmila Mitrović Institute of Meat Hygiene and Technology, Kaćanskog 13, 11000 Belgrade, Serbia Review of antimicrobial-resistant ESKAPEE pathogens in food sources and their relevance to the One Health approach person https://orcid.org/0000-0003-2912-2784 Brankica Lakićević Institute of Meat Hygiene and Technology, Kaćanskog 13, 11000 Belgrade, Serbia Review of antimicrobial-resistant ESKAPEE pathogens in food sources and their relevance to the One Health approach person https://orcid.org/0000-0002-0175-5830 Lazar Milojević Institute of Meat Hygiene and Technology, Kaćanskog 13, 11000 Belgrade, Serbia Review of antimicrobial-resistant ESKAPEE pathogens in food sources and their relevance to the One Health approach person https://orcid.org/0000-0001-6901-6033 application/pdf 434149 https://unilib.phaidrabg.rs/o:8611 no yes 16 70 92000002 71A01 Meat technology - Special Issue 66/3 2025 1-576 66 3 295 300 Kaćanskog 13, 11 000 Belgrade Institute of Meat Hygiene and Technology 2025-12-01 www.journalmeattechnology.com