o:8521 Metal bioaccumulation in fish species from the Danube River in Serbia and evaluation of possible health risks en The aim of the present study was to assess the content of metals in fish meat and to evalu‑ ate possible health risks from dietary consumption of fish caught from the Danube River in Serbia in the past fifteen years. Therefore, the metal pollution index (MPI) and the fol‑ lowing health risk indexes were calculated: estimated daily intake (EDI), estimated weekly intake (EWI), % of provisional tolerable weekly intake (% PTWI), target hazard quotient (THQ), hazard index (HI), and target cancer risk (TR). Levels of Cd in common carp and Wels catfish from 2011 to 2013 and in silver carp in 2021 exceeded maximum allowed con‑ centrations in fish meat. Wels catfish contained higher contents of Hg from 2011 to 2013 and Pb in 2010 than prescribed by the national regulation. Moreover, MPIs determined for common carp, Wels catfish, and barbel gradually decreased during the observed period, except for silver carp where a slight increasing trend was observed. The HI was higher than 1 in almost all studies, and exceeded maximum allowed levels prescribed by international and national regulations. In all presented studies, TR was lower than the acceptable lifetime risk (ARL) of 10 −4 , except for As in common carp caught in Zemun and Grocka during 2013 when an unacceptable carcinogenic risk (> 10 −4 ) was detected (1.10 x10 −4 and 1.43 x10 −4 , respectively). It is necessary to implement regular monitoring of metal levels in fish from the Danube River in order to preserve human and environmental health. Danube River, Common carp, Wels catfish, Silver carp, Barbel 1552099 https://doi.org/10.18485/meattech.2025.66.1.6 2025-11-27T08:37:19.507Z 44 yes 46 Marija Starčević Veterinary Service Centre, Military Health Department, Ministry of Defence of Republic of Serbia, Crnotravska 17, Belgrade 11000, Serbia Metal bioaccumulation in fish species from the Danube River in Serbia and evaluation of possible health risks https://orcid.org/0000-0002-0857-5218 Nenad Katanić Ministry of Agriculture, Forestry and Water Management of Republic of Serbia, Omladinskih brigada 1, Belgrade 11000, Serbia Metal bioaccumulation in fish species from the Danube River in Serbia and evaluation of possible health risks person https://orcid.org/0000-0001-5983-231X Milica Laudanović University of Belgrade, Faculty of Veterinary Medicine, Bulevar Oslobodjenja 18, Belgrade 11000, Serbia; Metal bioaccumulation in fish species from the Danube River in Serbia and evaluation of possible health risks person https://orcid.org/0009-0008-6381-2803 Dragoljub Jovanović University of Belgrade, Faculty of Veterinary Medicine, Bulevar Oslobodjenja 18, Belgrade 11000, Serbia; Metal bioaccumulation in fish species from the Danube River in Serbia and evaluation of possible health risks person https://orcid.org/0000-0003-1665-7106 Aleksandra Tasić Scientific Institute of Veterinary Medicine of Serbia, Janisa Janulisa 14, 11000 Belgrade, Serbia Metal bioaccumulation in fish species from the Danube River in Serbia and evaluation of possible health risks person https://orcid.org/0000-0002-8361-5697 Branislav Baltić Institute of Meat Hygiene and Technology, Kaćanskog 13, 11000 Belgrade, Serbia Metal bioaccumulation in fish species from the Danube River in Serbia and evaluation of possible health risks person https://orcid.org/0000-0003-2603-2521 Nataša Glamočlija University of Belgrade, Faculty of Veterinary Medicine, Bulevar Oslobodjenja 18, Belgrade 11000, Serbia Metal bioaccumulation in fish species from the Danube River in Serbia and evaluation of possible health risks person https://orcid.org/0000-0003-4799-9416 application/pdf 789890 https://unilib.phaidrabg.rs/o:8521 no yes 16 70 92000001 71A01 Meat technology 66 1 53 63 Meat technology Kaćanskog 13, 11 000 Belgrade Institute of Meat Hygiene and Technology 2025-06 www.journalmeattechnology.com