o:8017 Health profile of the selected pharmaceutical pollutants in the aquatic environment en This article investigated whether pharmaceuticals such as Carbamazepine and 4-AAA (4- acetyl-amino-antipyrine) as water pollutants can cause health issues and toxicological risks. The OPERA models were used for detail characterization of pharmacokinetic profile and the SILIS- PTOXRA software was used to predict acute based toxicity on multiple linear regression models. The results indicate increased concentrations in the liver and organs of the fetus after consuming contaminated water. In addition, significant effects on aquatic organisms are also expected. Pharmaceutical pollutants; aquatic environment; health effect; ecopharmacovigilance 1552100 978-86-6022-733-3 2025-07-25T08:51:43.578Z 44 no 46 Tatjana Mitrović Institute of Physics Belgrade, University of Belgrade, Belgrade, Serbia Darija Obradović Institute of Physics Belgrade, University of Belgrade, Belgrade, Serbia person Lazović Saša Institute of Physics Belgrade, University of Belgrade, Belgrade, Serbia person Marija Perović Jaroslav Černi Water Institute, Belgrade, Serbia person 0000-0003-2045-001X application/pdf 601187 https://unilib.phaidrabg.rs/o:8017 no yes 1 70 92000004 71A04 Proceedings 3rd International EUROSA Conference, May 14-17, 2025, Vrnjačka Banja, Serbia 9 15 Faculty of Technical Sciences, Novi Sad, Republic of Serbia 2025