o:7747 FORMULATION OF HONEY-BASED SUPPLEMENT ENRICHED WITH MICROENCAPSULATED CHOKEBERRY POMACE EX en The aim of the study was to obtain an added-value supplement based on honey and microencapsulated chokeberry pomace extract. The fruits were pressed to obtain juice pomace. The influence of different temperatures and length of drying of the pomace on the content of bioactive ingredients was examined and the following conditions were chosen as optimal: a temperature of 45°C; drying time of 36 hours. After extraction optimization the following parameters were selected as optimal: extraction time of 90 minutes, 50% ethanol and a ratio of drug to solvent of 1:10. The quantification of individual anthocyanins (cyanidin galactoside, cyanidin glucoside, cyanidin arabinoside and cyanidin xyloside) was performed using HPLC where cyanidin galactoside was the most abundant (6.82±0.06 mg/g). Carriers based on hydrogels or waxes with or without addition of inulin were tested using by electrostatic extrusion encapsulation technique. Also, various process parameters that influenced the microencapsulation process were analyzed. A medium-viscosity alginate with 5% inulin was selected as carrier. Encapsulation efficiency, cyanidin galactoside release from microparticles, particle size, FTIR and SEM analysis were done. Two types of particles were prepared, i.e. non-dried and dried particles. The lyophilization conditions were optimized for drying of microparticles. During formulation, three types of honey were tested: acacia, meadow and linden. Formulations were made with 3%, 5%, 7%, 10% and 20% of microparticles in honey, with and without heating at 2 temperatures (35 and 450C). Final formulation was prepared with acacia honey, 10% of undried microparticles with heating of honey on a temperature of 35°C. 1552101 2682-9487 2025-06-02T10:48:19.551Z 44 no 46 Katarina Šavikin Institute for Medicinal Plant Research ''Dr. Josif Pančić'' Belgrade 0000-0002-2086-9593 46 Nada Ćujić Nikolić Institute for Medicinal Plants Research "Dr Josif Pančić" Belgrade 0000-0002-6736-3637 46 Gordana Zdunić Institute for Medicinal Plants Research "Dr Josif Pančić" Belgrade 0000-0002-5793-3739 46 Jelena Živković Institute for Medicinal Plant Research, ''Dr. Josif Pančić'' Belgrade 0000-0002-9684-2637 46 Branko Bugarski Faculty of technology and metallurgy, University of Belgrade application/pdf 3280752 https://unilib.phaidrabg.rs/o:7747 no yes 1 70 92000004 71A10 BOOK OF ABSTRACTS 6 International conference on natural products utilization PP100 255 255 From plants to pharmacy shelf 2025