o:7487 EFFECTS OF CHOKEBERRY AND TART CHERRY BASED DIETARY SUPPLEMENTS IN DYSLIPIDEMIC INDIVIDUALS en The prevalence of obesity has increased dramatically over the last several decades. It is estimated the United States approximately 40% of women and 35% of men are obese (BMI >30 kg/m2). It is of great concern is that the prevalence of obesity has also markedly increased in children. Obesity is associated with alterations in lipid metabolism, insulin resistance and metabolic syndrome, particularly when the excess adipose tissue is located in an intra-abdominal location or in the upper chest. Moreover, obesity is a great risk factor for the development of cardiovascular disease. Epidemiological studies indicated that high intake of dietary polyphenols is connected with lower risk for development of chronic diseases such as cardiovascular, diabetes, obesity, neurodegenerative. That is why polyphenols are nowadays common ingredients in lot of dietary supplements and functional foods. Polyphenols are plant secondary metabolites widely distributed in medicinal plants, red wine, many fruits and vegetables, and their derived products. According to some researches, there is 200−300 mg of dietary polyphenols in every 100 g of fresh fruits or vegetables, and the total dietary intake of polyphenols in adults is from 700 to 1700 mg/day. Various bioactivities are connected with polyphenols such as antioxidant, antimicrobial, anti-inflammatory, antineurodegenerative, anticancer, antidiabetic, antiaging etc. Previous studies showed that consumption of Aronia melanocarpa extract is correlated with a positive effect on body weight, total cholesterol, low and high-density lipoproteins. The aim of our study was to evaluate the effect of combined oral consumption of two dietary supplements based on chokeberry and tart cherry juices over a period of 90 days on cholesterol, LDL, HDL, triglycerides, thickness of subcutaneous fatty tissue in different areas and safety in 46 participants with dyslipidemia. At the level of individual respondents 11 respondents (24%) had a significant improvement in cholesterol, HDL and LDL, 10 respondents (22%) had an improvement in cholesterol and LDL while there was an improvement in triglycerides in 19 subjects (41%). Although a slight decrease in cholesterol, HDL, LDL, and triglyceride levels was observed at the group level, it was not statistically significant. On the other hand, statistically significant improvement (decrease) was recorded in the thickness of subcutaneous fatty tissue in different areas i.e. in the middle of the front abdominal wall (right and left) and in the middle of the front side of the thigh (right and left). Moreover, statistically significant improvement in BMI (body mass index) was recorded from 36.53±10.72 to 30.33±6.70 (p-value 0.0001). The levels of creatinine, urea, ALT and AST values which remained within normal limits, indicated that dietary supplements did not have negative effects on the liver and kidneys during the study. chokeberry, tart cherry, juices, dyslipidemia, obesity 1552100 978-86-7520-629-3 2025-04-16T13:17:45.027Z 44 no 46 Dubravka Bigović Institute for Medicinal Plant Research ''Dr. Josif Pančić'' Belgrade 0000-0003-1999-2743 46 Katarina Šavikin Institute for Medicinal Plants Research "Dr Josif Pančić" Belgrade 0000-0002-2086-9593 46 Nemanja Krgović Institute for Medicinal Plants Research "Dr Josif Pančić" Belgrade 0000-0003-3611-9911 46 Jelena Živković Institute for Medicinal Plant Research, ''Dr. Josif Pančić'' Belgrade 0000-0002-9684-2637 application/pdf 1192307 https://unilib.phaidrabg.rs/o:7487 no yes 1 70 92000004 71A10 BOOK OF ABSTRACTS PTEP 2025 5 6 NINTH INTERNATIONAL CONFERENCE SUSTAINABLE POSTHARVEST AND FOOD TECHNOLOGIES INOPTEP 2025 and XXXVII NATIONAL CONFERENCE PROCESSING AND ENERGY IN AGRICULTURE 2025