o:6315 NATURAL DEEP EUTECTIC SOLVENTS – A PROMISING MEDIA TOWARDS SUSTAINABLE VALORISATION OF UNDERUTILIZED CROPS en Diversifying food resources through incorporation of crops with nutritional and health benefits present a promising strategy in sustaining nutraceutical security under climate change and biodiversity degradation. Buckwheat is such underutilized crop, known for the abundance of bioactive compounds that have a vast potential to support human health. Heat-assisted extraction supported with natural deep eutectic solvents (NaDES) was employed to extract polyphenols from the Fagopyrum esculentum Moench. Response surface methodology was used to optimize the extraction process, considering results obtained in the screening assay with nine different NaDES. In screening analysis, lactic acid-containing NaDES showed the highest extraction capacity for rutin, whereas total flavonoids were favorably extracted by choline chloride/propylene glycol (ChCl/PG) mixture. The optimal conditions for the highest flavonoid content in ChCl/PG extraction were 64.87°C, 112.61 min, and 30.92% of water. Extracts obtained through implementation of green extraction procedures from buckwheat holds a great potential to contribute to the consumers’ nutrient and health benefits and pave the way for incorporation into the new natural-based products. 1552099 10.60738/03ak-mn82 2024-12-04T07:48:50.709Z 44 no 46 Milica Radan Institute for Medicinal Plant Research, ''Dr. Josif Pančić'' Belgrade 0000-0002-6727-7624 46 Miloš Jovanović University of Niš, Faculty of Medicine, Department of Pharmacy 46 Nemanja Krgović Institute for Medicinal Plants Research "Dr Josif Pančić", Belgrade 0000-0003-3611-9911 46 Katarina Šavikin Institute for Medicinal Plant Research, ''Dr. Josif Pančić'' Belgrade 0000-0002-2086-9593 application/pdf 739134 https://unilib.phaidrabg.rs/o:6315 no yes 1 70 92000004 71A10 Abstracts Book 125 125 17th World Congress on Polyphenols Aplications 2024