http://creativecommons.org/licenses/by/4.0/legalcode Abstract: This research aimed to determine the prevalence rate of antimicrobial resistance (AMR) of Staphylococcus aureus isolated from raw cow milk samples in Albania and Serbia. A total of 100 raw milk samples, 50 from Albania and 50 from Serbia, have been collected from randomly selected cattle farms. Twelve samples (12%) were positive for S. aureus, five of those originating from Albania (41.66%) and seven from Serbia (58.33%). Resistance of isolated S. aureus strains to ampicillin in milk samples from Albania (36.7%) and Serbia (34.1%) was the most common. Some of S. aureus strains from milk samples from Albania were resistant to tetracycline (16.9%), while isolates from milk samples from Serbia were more resistant towards oxacillin (18%). The recorded resistance towards erythromycin (13.2%; 13.1%), and sulfatrim (7.6%; 6.9%) was similar between both milk samples, respectively. The obtained results have shown higher resistance of S. aureus strains towards cephalothin in milk samples from Serbia (3.9%) compared to milk samples from Albania (1.6%), respectively. All isolates tested for antibiotic sensitivity were susceptible to methicillin, vancomycin, chloramphenicol, and ciprofloxacin. The obtained results regarding the minimum inhibitory concentrations (MICs) of antibiotics indicated that isolates were resistant to tetracycline, oxacillin, erythromycin, and ampicillin, respectively. Results of our investigation have shown that the found antibiotics residues are related to the usage of erythromycin (72.6% and 73.9%), followed by ampicillin (70.4% and 71.2%) while residues of ciprofloxacin in the analysed milk samples was not registered. Sažetak: Cilj ovog istraživanja bio je utvrditi stopu prevalencije antimikrobne rezistencije (AMR) Staphylococcus aureus izoliranog iz uzoraka sirovog kravljeg mlijeka u Albaniji i Srbiji. Na nasumično odabranim farmama krava prikupljeno je ukupno 100 uzoraka sirovog mlijeka, 50 iz Albanije i 50 iz Srbije. Dvanaest uzoraka (12 %) je bilo pozitivno na S. aureus, od čega je pet bilo porijeklom iz Albanije (41,66 %) i sedam iz Srbije (58,33%). Rezistentnost izoliranih sojeva S. aureus na ampicilin u oba uzorka mlijeka iz Albanije (36,7 %) i Srbije (34,1 %) bio je najčešći. Neki sojevi S. aureus iz uzoraka mlijeka iz Albanije bili su rezistentni na tetraciklin (16,9 %), dok su izolati iz uzoraka mlijeka iz Srbije bili rezistentni na oksacilin (18 %). Zabilježena rezistencija na eritromicin (13,2 %; 13,1 %) i sulfatrim (7,6 %; 6,9 %) bila je slična između oba uzorka mlijeka. Dobiveni rezultati pokazali su veću rezistentnost sojeva S. aureus prema cefalotinu u uzorcima mlijeka iz Srbije (3,9 %), u odnosu na uzorke mlijeka iz Albanije (1,6 %). Svi izolati testirani na rezistentnost na antibiotike bili su osjetljivi na meticilin, vankomicin, kloramfenikol i ciprofloksacin. Rezultati dobiveni određivanjem minimalnih inhibitornih koncentracija (MIC) antibiotika pokazali su da su izolati rezistentni na tetraciklin, oksacilin, eritromicin i ampicilin. Rezultati našeg istraživanja pokazali su kako su pronađeni ostaci antibiotika povezani s upotrebom eritromicina (72,6 % i 73,9 %) i ampicilina (70,4% i 71,2%), dok ostaci ciprofloksacina u ispitivanim uzorcima mlijeka nisu registrirani. https://unilib.phaidrabg.rs/o:5722 doi:10.15567/mljekarstvo.2021.0404 Keywords milk; milk safety; AMR; antibiotics; S. aureus Ključne riječi: mlijeko, sigurnost mlijeka, AMR; antibiotici, S. aureus. application/pdf 459320 bytes Lika, Erinda Rosić, Milovan Cocoli, Sonila Puvača, Nikola Vuković, Gorica Shtylla Kika, Tana Bursić, Vojislava Antimicrobial resistance of Staphylococcus aureus strains isolated from cow raw milk samples from Albania and Serbia Antimikrobna rezistencija sojeva Staphylococcus aureus izoliranih iz uzoraka sirovog kravljeg mlijeka s područja Albanije i Srbije Mljekarstvo volume: 71 number: 4 startpage: 248 endpage: 256 info:eu-repo/semantics/article 2021-10-08 eng