o:5375 Toxicological assessment of honey from conventional and organic production and risk assessment for public health Toksikološka procena meda iz konvencionalne i organske proizvodnje i procena rizika za javno zdravlje stanovništva en Abstract: Honey has become a focal point of concern due to the potential presence of pesticide residues originating from agricultural practices. This study undertakes a comprehensive toxicological assessment of pesticide residues in conventional and organic honey, as well as a risk assessment employing estimated daily intakes (EDIs) in the evaluation of the potential risks of these agrochemicals to public health. A total of 200 honey samples originating from conventional and organic producers were collected and analyzed by a Quick Easy Cheap Effective Rugged Safe method (QuEChERS). Analysis of organic honey didn’t detect any residue of investigated pesticides. The most detected pesticides in conventional honey samples were boscalid (0.01 µg/kg), and coumaphos ranging between 0.012 µg/kg to 0.016 µg/ kg, respectively. Detected pesticides such as acetamiprid, pyraclostrobin, thiacloprid, and azoxystrobin were under the reporting level (RL). Results obtained by EDI indicated that all investigated honey samples are safe for human consumption. In conclusion, this research contributes to the understanding of the toxicological implications of pesticide residues in both conventional and organic honey consumption. By delineating the potential health hazards associated with each type, this study aims to provide consumers, regulators, and beekeeping industries with valuable insights to make informed decisions that safeguard human health while promoting sustainable agricultural practices. Sažetak: Med je postao fokus zabrinutosti zbog potencijalne prisutnosti ostataka pesticida. Cilj ovog rada je toksikološka procena ostataka pesticida u konvencionalnom i organskom medu, kao i procena rizika primenom procenjenih dnevnih unosa (EDI) po javno zdravlje stanovništva. Ukupno 200 uzoraka meda poreklom od konvencionalnih i organskih proizvođača prikupljeno je i analizirano pomoću Quick Easy Cheap Effective Rugged Safe (QuEChERS) metode. Analiza organskog meda nije zabeležila ostatke ispitivanih pesticida. Najviše detektovani pesticidi u uzorcima konvencionalnog meda su bili boskalid (0,01 µg/kg) i kumafos, u rasponu od 0,012 µg/kg do 0,016 µg/kg. Pesticidi poput acetamiprida, piraklostrobina, tiakloprida i azoksistrobina bili su ispod nivoa izveštavanja (<RL). Rezultati dobijeni putem EDI ukazuju da su svi ispitivani uzorci meda bezbedni za konzumaciju ljudi. Na osnovu dobijenih rezultata može se zaključiti, da ovo istraživanje doprinosi razumevanju toksikoloških posledica ostataka pesticida u konzumaciji kako konvencionalnog, tako i organskog meda. Proučavanjem potencijalnih zdravstvenih opasnosti, ovo istraživanje ima za cilj da pruži potrošačima, regulatornim telima, kao i pčelarima značajne informacije za donošenje odluka koje čuvaju ljudsko zdravlje promovišući istovremeno održivu poljoprivrednu proizvodnju. Keywords: honey, pesticides, toxins, bees, public health, risk assessment Ključne reči: med, pesticidi, toksini, pčele, javno zdravlje, procena rizika 1552099 10.5513/jcea01/25.2.4210 2024-09-23T10:29:38.160Z 44 yes 46 Nikola Puvača Fakultet za ekonomiju i inženjerski menadžment u Novom Sadu 0000-0002-5500-7010 Vojislava Bursić person Ivana Brkić Fakultet za ekonomiju i inženejrski menadžment u Novom Sadu person 0000-0002-5319-7893 Jelena Vapa Tankosić Fakultet za ekonomiju i inženjerski menadžment u Novom Sadu person 0000-0001-8062-1154 Radivoj Prodanović Fakultet za ekonomiju i inženjerski menadžment u Novom Sadu person 0000-0002-7088-8506 Gorica Vuković person application/pdf 880092 https://unilib.phaidrabg.rs/o:5375 no yes 16 70 1552253 2024-01-11 Journal of Central European Agriculture 25 2 554 566 2024