o:484 Chemical composition of the alkaloid extracts isolated from Hylotelephium spectabile (Boreau) H. Ohba x telephium (L.) H. Ohba aerial parts en Abstract: There are many motives to study alkaloids within Crassulaceae family, such as chemotaxonomic consideration of alkaloid distribution and evaluation of their biological potential. Data on alkaloids from Sedum telephium (syn. H. telephium) aroused interest for further alkaloid investigation within the genus Hylotelephium H. Ohba. Thus, the aim of this study was to investigate and characterize other plant sources of alkaloids from the same genus. An alkaloid extract (AE-HS) was isolated from fresh aerial parts of a cultivated hybrid H. spectabile x telephium. The chemical composition of AE-HS was determined by GC-MS (gas chromatography – mass spectrometry) method. Eight components were identified, which made up 91.8% of the sample. The most present component of AE-HS was γ-crotonolactone (78.6%) followed by 3-methyl-2-butenal (8.6%) and (E)-coniferyl alcohol (2.8%). Nicotine was identified as the only alkaloid in the AE-HS (0.4%). Along with many non-alkaloid compounds, a previous study found six alkaloids in AE of S. telephium (~7%), suggesting differences from our results. Additionally, alkaloid distribution is limited within other genera of the family and belonging to the same genus does not mean a uniform qualitative composition. Further analyzes of AEs of Hylotelephium taxa would certainly shed light on the pattern of alkaloid distribution. Keywords: Hylotelephium spectabile x telephium, alkaloids, GC-MS analysis 91552100 65979401 1552099 10.5937/savteh2102005D 2022-06-26T19:11:45.968Z 44 yes 46 Miloš G. Đukić Univerzitet u Nišu, Prirodno-matematički fakultet, Departman za hemiju ; University of Niš, Faculty of Science and Mathematics, Department of Chemistry Jelena M. Jovanović Univerzitet u Nišu, Prirodno-matematički fakultet, Departman za hemiju ; University of Niš, Faculty of Science and Mathematics, Department of Chemistry person Gordana S. Stojanović Univerzitet u Nišu, Prirodno-matematički fakultet, Departman za hemiju ; University of Niš, Faculty of Science and Mathematics, Department of Chemistry person Snežana Č. Jovanović Univerzitet u Nišu, Prirodno-matematički fakultet, Departman za hemiju ; University of Niš, Faculty of Science and Mathematics, Department of Chemistry person application/pdf 473076 https://unilib.phaidrabg.rs/o:484 no yes 1 70 92000004 Advanced technologies. - ISSN 2406-2979 10 2 5 8 2021