eng https://unilib.phaidrabg.rs/o:4655 doi:10.55817/YZFA3391 application/pdf 542646 bytes http://creativecommons.org/licenses/by/4.0/legalcode Colibacillosis in Modern Poultry Production Puvača, Nikola Kika, Tana Shtylla Cocoli, Sonila Ljubojević Pelić, Dragana Lika, Erinda Pelić, Miloš info:eu-repo/semantics/review Keywords: E. coli; colibacillosis; poultry; birds; diseases; virulence. 2023 Abstract: Colibacillosis, a bacterial infection caused by pathogenic Escherichia coli strains, poses significant challenges to contemporary poultry farming. This paper provides a succinct overview of key aspects related to the disease. Colibacillosis manifests with respiratory, enteric, and systemic clinical signs, impacting broilers, layers, and breeders. The etiology involves virulent E. coli strains with specific adhesion and invasion mechanisms. The avian immune response plays a crucial role, influenced by factors such as age, stress, and vaccination. The epidemiology exhibits global prevalence, influenced by geographical, seasonal, and farm-specific factors. Control strategies encompass biosecurity measures, vaccination, responsible antimicrobial use, genetic selection, and environmental management. Comprehensive understanding and proactive management of colibacillosis are essential to mitigate economic losses and sustain the health and productivity of poultry in modern production systems. In conclusion colibacillosis remains a significant challenge in modern poultry production, with economic implications for the industry. Efforts to control and manage colibacillosis in poultry production should take into consideration these multifaceted factors and focus on prevention, early detection, and responsible antimicrobial use. Colibacillosis in Modern Poultry Production vol. 6 br. 6 str. 975-987