All rights reserved Minerva cardioangiologica 68(5) eng Sandner, Sigrid E. Aschacher, Thomas Pachuk, Catherine J. Milojević, Milan Caliskan, Etem Emmert, Maximilian Y. application/pdf 359178 bytes https://unilib.phaidrabg.rs/o:3553 doi:10.23736/S0026-4725.20.05234-2 cobiss:128614153 ISSN: 1827-1618 Endothelial damage inhibitors for improvement of saphenous vein graft patency in coronary artery bypass grafting The saphenous vein graft (SVG) remains the most commonly used conduit in coronary artery bypass grafting (CABG). In light of this further research must be aimed at the development of strategies to optimize SVG patency and thereby improve both short- and long-term outcomes of CABG surgery. SVG patency in large part depends on the protection of the structural and functional integrity of the vascular endothelium at the time of conduit harvesting, including optimal storage conditions to prevent endothelial damage. This review provides an overview of currently available storage and preservation solutions, including novel endothelial damage inhibitors, and their role in mitigating endothelial damage and vein graft failure. 2020 Key words: coronary artery bypass, saphenous vein, coronary artery disease, vascular grafting info:eu-repo/semantics/article