2021 Tanasković, Slobodan Gajin, Predrag Ilić, Miodrag Matić, Predrag Kovačević, Vladimir Atanasijević, Igor Babić, Srđan Ilijevski, Nenad eng https://unilib.phaidrabg.rs/o:3032 doi:10.2298/SARH210121060T cobiss:49485833 ISSN: 0370-8179 Srpski arhiv za celokupno lekarstvo 149(9/10) Spleen-preserving surgical treatment of splenic artery aneurysm secondary to chronic pancreatitis and primary biliary cholangitis http://creativecommons.org/licenses/by-nc/4.0/legalcode https://scindeks.ceon.rs/journaldetails.aspx?issn=0370-8179 Keywords: splenic artery aneurysm, chronic pancreatitis, primary biliary cholangitis, spleen-preservation surgery INTRODUCTION: Splenic artery aneurysm (SAA) represents the third cause of abdominal aneurysms, just after abdominal aorta and iliac arteries aneurysms, with overall prevalence of 1%. Pancreatitis has been linked with pseudoaneurysm formation of SA due to destruction of arterial wall by pancreatic enzymes, however true SAA associated with pancreatitis has not been described yet. We are presenting the first case of true SAA in a patient with chronic pancreatitis and primary biliary cholangitis successfully treated by surgical excision, direct arterial reconstruction and spleen preservation. CASE OUTLINE: A 74-years-old male patient was admitted for multidetector computed tomography angiography due to suspected SAA and renal artery aneurysm (RAA). He was previously treated for chronic pancreatitis and primary biliary cholangitis. Upon admission, computed tomography arteriography showed SAA 32 mm in diameter and RAA 12 mm with SAA being in direct contact with superior margin of the pancreas. Surgical treatment of SAA was indicated while RAA was treated conservatively. Intraoperatively, SAA adherent to the superior margin of pancreas was noted, followed by complete exclusion of the aneurysm and end-to-end splenic artery anastomosis. Histopathology showed atherosclerotic degeneration of arterial wall with all three layers presenting as true aneurysm. Two years after the surgery, control computed tomography angiography showed regular postoperative findings without further progression of RAA. CONCLUSION: This is the first case to describe a true SAA aneurysm originated on the field of previous episodes of chronic pancreatitis and primary biliary cholangitis. Surgical treatment including aneurysm resection and direct arterial reconstruction with spleen preservation showed satisfactory results. info:eu-repo/semantics/article application/pdf 1542663 bytes