o:2911 Endovascular treatment of symptomatic high-grade vertebral artery stenosis en BACKGROUND: The purpose of this study was to evaluate the initial and long-term results of endovascular treatment (EVT) in patients with symptomatic high-grade extracranial vertebral artery (VA) origin stenosis. METHODS: From February 2001 to March 2013, 73 consecutive patients (33 men with a mean age of 61.7 6 8.8 years) underwent EVT for symptomatic high-grade VA stenosis. Preoperative evaluation included Duplex ultrasonography and arteriography. After successful treatment, all patients were followed up at 1, 3, 6, and 12 months after the procedure and every 6 months thereafter. RESULTS: Successful EVT of the VA stenosis was achieved in 68 patients (93.2%). All procedures were performed without use of cerebral protection. The early complication rate was 5.5%, which included one periprocedural transient ischemic attack, two hematomas at the puncture site, and one allergic reaction to the contrast agent. No in-hospital deaths occurred. During follow-up (mean, 44.3 6 31.2 months; range, 2-144 months), the primary patency rates at 1, 3, 5, and 7 years were 98.4%, 87.3%, 87.3%, and 87.3%, respectively. Ultrasound Doppler controls during follow-up detected seven VA restenoses (10.3%). Univariate analysis failed to identify any variable predictive of long-term patency of successfully treated VA stenosis. CONCLUSION: EVT of symptomatic VA origin stenosis is a safe and effective procedure associated with low risk and good long-term results, even without use of cerebral protection devices. Accepted version Key words: vertebral arterystenosis, endovascular treatment 91552100 125855241 1552101 0741-5214 1552099 10.1016/j.jvs.2014.01.023 2023-10-04T11:42:26.668Z 44 yes 46 Đorđe Radak 12465767 0000-0003-3199-5613 2014 46 Dragan Sagić 12513127 0009-0002-2516-6480 2014 46 Srđan Babić 19073383 0000-0001-9659-9190 2014 46 Slobodan Tanasković 19201127 0000-0003-4216-6693 2014 46 Vladimir Kovačević 76177161 0000-0002-7165-6096 2014 46 Petar Otašević 12787303 0000-0002-0362-5765 2014 46 Zoran Rančić 8553831 0000-0003-2001-4015 2014 application/pdf 310406 https://unilib.phaidrabg.rs/o:2911 no yes 18 Podaci o licenci prema https://v2.sherpa.ac.uk/id/publication/3223 70 616.13-007.271-08 92000001 71A11 Journal of Vascular Surgery 60 1 92 97 2014