o:2819 Comparative evaluation of toxicology and sociodemographic characteristics in homicide and suicide victims en BACKGROUND/AIM: Suicide and homicide are very important social problem, especially frequent among the population younger than 40 years old. The aim of this study was to assess the influence of different sociodemographic factors and relevant psychoactive substances on the difference between homicide and suicide victims. METHODS: A cross - sectional study analysed autopsy reports of 714 suicide cases and 166 homicide cases, autopsied in a five-year period (2011-2016). Out of these, 666 suicide cases and 127 homicide cases met the inclusion criteria for this study. Blood-ethanol concentration was determined by headspace gas chromatography with flame ionisation detection (HS-GCFID). Analysis of substances other than ethanol was accomplished by gas chromatographymass spectrometry (GC-MS) and liquid chromatography tandem-mass spectrometry (LCMS/MS).Results. There was a significant difference in age, level of education and employment rate between suicide and homicide cases (p < 0.05). The distribution of suicide and homicide cases differed significantly on weekdays in comparison to weekends (OR=1.5; 95 % CI=1 – 2.3; p < 0.05). Presence of a psychoactive substance remained a non - significant predictor of whether a person would become a homicide or suicide victim (p > 0.05). Homicide victims were more likely to have significantly higher blood alcohol concentration (0.2 – 0.3 g/dL) than suicide victims (OR=2.2; 95 % CI=1 - 5; p < 0.05). CONCLUSION: Victim's age, level of education, employment status and high blood alcohol concentration (0.2 – 0.3 g/dL) are significantly different between suicide and homicide cases. Preprint Key words: autopsy alcohol drinking, chromatography, education, homicide, risk factors, sex factors, sociodemographic factors, suicide, substance related disorders Kdljučne reči: autopsija, alkohol, pijenje, hromatografija, obrazovanje, ubistvo, faktori rizika, pol faktor, socijalno-demografski faktori, samoubistvo, poremećaji izazvani supstancama 91552100 125371145 1552101 2406-0720 1552099 10.2298/VSP220320061B 2023-09-27T08:52:08.707Z 44 yes 46 Milenko Bogdanović 30815591 0000-0002-4471-5011 2023 46 Miloš D. Babić 104886537 0000-0002-3226-003X 2023 46 Dušan Janković 104888585 0009-0009-7623-7331 2023 46 Bojana Radnić 56595721 0000-0001-9854-2649 2023 46 Tijana Aćimović 104891913 2023 46 Đorđe Alempijević 12732775 0000-0002-0810-9559 2023 46 Snežana Pavlekić 12668263 0000-0002-2234-7625 2023 application/pdf 333904 https://unilib.phaidrabg.rs/o:2819 no yes 1 70 616.89-008.441.44:615.9340.62:615.9:31 92000001 71A11 Vojnosanitetski pregled 80 4 330 336 2023