
<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/">
  <dc:creator>Menković, Nebojša</dc:creator>
  <dc:creator id="https://orcid.org/0000-0003-1761-604X">Tadić, Vanja</dc:creator>
  <dc:source>Natural Medicinal Materials - Lekovite sirovine(41)</dc:source>
  <dc:format>application/pdf</dc:format>
  <dc:format>8385083 bytes</dc:format>
  <dc:title xml:lang="eng">Comprehensive combined chemical and pharmacognostic approach in the investigation of Montenegrin flora, with emphasis on endemic species: Past performance and future potential</dc:title>
  <dc:date>2021</dc:date>
  <dc:language>eng</dc:language>
  <dc:subject xml:lang="eng">Combined pharmacognostic and chemical research; Swertia, Gentiana, Gentianella, Anthemis and Tanacetum species; oxygenated xanthones; sesquiterpene lactones, taxonomic markers; structure-activity investigation of secondary metabolites</dc:subject>
  <dc:description xml:lang="eng">Herein, we have reviewed the comparative analysis relating pharmacognostic and chemical approaches
in the investigation of the chosen plants from Montenegrin flora known for the constituents recognized
as carriers of different biological activities. In addition, some of the mentioned extensively studied
plants were with uncertain status in the systematics, as not being recognized as new species. The
results of pharmacognostic studies with the thorough chemical analyses addressing the problem in
positioning some of the investigated plants from Swertia, Gentiana and Gentianella genera belonging
to family Gentianaceae in systematics, performed within the collaboration of two research groups from
Institute for Medicinal Plants Research “Dr. Josif Panˇci´c” and Faculty of Chemistry, the University
of Belgrade under the leadership of Dr. Nebojša Menkovi´c and Prof. Dr. Slobodan Milosavljevi´c
were summarized. In addition, the complete chemical structure elucidation of sesquiterpene lactones
present in Anthemis sp. as potential anti-inflammatory agents, applying the sophisticated 2D NMR
techniques was reviewed. Further, the parthenolide content determination in Tanacetum larvatum
revealed the possibility of the successful application of 1H NMR techniques in quantification studies.
The findings presented in the published literature stressed the importance of a combined chemical and
pharmacognostic approach in the investigation of natural products originating from plants</dc:description>
  <dc:identifier>https://unilib.phaidrabg.rs/o:2726</dc:identifier>
  <dc:identifier>doi:10.5937/leksir2141106M</dc:identifier>
  <dc:identifier>ISSN: 0455-6224</dc:identifier>
  <dc:rights>All rights reserved</dc:rights>
  <dc:type>info:eu-repo/semantics/review</dc:type>
</oai_dc:dc>