
<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/">
  <dc:identifier>https://unilib.phaidrabg.rs/o:2593</dc:identifier>
  <dc:identifier>doi:10.1016/j.foodchem.2022.134816</dc:identifier>
  <dc:identifier>ISSN: 0308-8146</dc:identifier>
  <dc:description xml:lang="eng">Innovative eco-friendly methods based on natural deep eutectic solvents (NaDES) coupled with ultrasoundassisted
extraction were employed for chokeberry anthocyanins extractions. Nine different NaDES composed
of choline chloride as a hydrogen bond acceptor and organic acids (lactic, citric, malic), sugars (glucose, fructose),
polyols (glycerol, 1,2-propanediol, sorbitol), and an amide (urea) as hydrogen bond donors were screened.
Malic acid-containing NaDES was selected for optimization extraction conditions (time, temperature, water in
NaDES) by response surface methodology. Optimal conditions for simultaneously maximizing the anthocyanins
extraction (cyanidin-3-O-glucoside, cyanidin-3-O-galactoside, cyanidin-3-O-arabinoside, total anthocyanins)
were 42.7 ◦C, 90 min, and 40 % (w/w) water in NaDES. In the next stage of this study, the possibility to improve
anthocyanins extraction at elevated temperatures by incorporating different concentrations of hydroxypropyl-
β-cyclodextrin into selected NaDES was investigated. The extraction was improved at hydroxypropyl-β-cyclodextrin
concentrations up to 3 % (w/w). To clarify the interaction of NaDES components and anthocyanins, a
molecular dynamic simulation was conducted.</dc:description>
  <dc:language>eng</dc:language>
  <dc:date>2023</dc:date>
  <dc:source>Food Chemistry 405(134816)</dc:source>
  <dc:type>info:eu-repo/semantics/article</dc:type>
  <dc:creator id="https://orcid.org/0000-0003-0039-0929">Jovanović, Miloš</dc:creator>
  <dc:creator id="https://orcid.org/0000-0003-3611-9911">Krgović, Nemanja</dc:creator>
  <dc:creator id="https://orcid.org/0000-0002-6727-7624">Radan, Milica</dc:creator>
  <dc:creator id="https://orcid.org/0000-0002-6736-3637">Ćujić Nikolić, Nada</dc:creator>
  <dc:creator id="https://orcid.org/0000-0002-6695-2907">Mudrić, Jelena</dc:creator>
  <dc:creator id="https://orcid.org/0000-0002-0741-2337">Lazarević, Zorica</dc:creator>
  <dc:creator id="https://orcid.org/0000-0002-2086-9593">Šavikin, Katarina</dc:creator>
  <dc:subject xml:lang="eng">Aronia melanocarpa Anthocyanins NaDES Hydroxypropyl-β-cyclodextrin Molecular dynamic Green extraction Chemical compounds studied in this article: Cyanidin-3-O-galactoside (PubChem CID 441699) Cyanidin-3-O-glucoside (PubChem CID 441667) Cyanidin-3-O-arabinoside (PubChem CID 91810602) Choline chloride (PubChem CID 6209) Malic acid (PubChem CID 525) Hydroxypropyl-β-cyclodextrin (PubChem CID 14049689)</dc:subject>
  <dc:title xml:lang="eng">Natural deep eutectic solvents combined with cyclodextrins: A novel strategy for chokeberry anthocyanins extraction</dc:title>
  <dc:rights>All rights reserved</dc:rights>
  <dc:format>application/pdf</dc:format>
  <dc:format>632184 bytes</dc:format>
</oai_dc:dc>