o:1652 Landscape of Stress Response and Virulence Genes Among Listeria monocytogenes Strains en The pathogenic microorganism Listeria monocytogenes is ubiquitous and responsible for listeriosis, a disease with a high mortality rate in susceptible people. It can persist in different habitats, including the farm environment, the food production environments, and in foods. This pathogen can grow under challenging conditions, such as low pH, low temperatures, and high salt concentrations. However, L. monocytogenes has a high degree of strain divergence regarding virulence potential, environmental adaption, and stress response. This review seeks to provide the reader with an up-to-date overview of clonal and serotype-specific differences among L. monocytogenes strains. Emphasis on the genes and genomic islands responsible for virulence and resistance to environmental stresses is given to explain the complex adaptation among L. monocytogenes strains. Moreover, we highlight the use of advanced diagnostic technologies, such as wholegenome sequencing, to fine-tune quantitative microbiological risk assessment for better control of listeriosis. L. monocytogenes, stress genes, genomic islands, diversity, lineages, clonal complexes, low pH, persistence 1552099 10.3389/fmicb.2021.738470 2023-04-12T08:53:46.856Z 44 yes 46 Brankica Z. Lakićević Institute of Meat Hygiene and Technology Landscape of Stress Response and Virulence Genes Among Listeria monocytogenes Strains 0000-0002-0175-5830 Heidy M. W. den Besten Food Microbiology, Wageningen University and Research Landscape of Stress Response and Virulence Genes Among Listeria monocytogenes Strains person Daniela De Biase Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy person 2022 application/pdf 1848137 https://unilib.phaidrabg.rs/o:1652 no yes 1 70 1552253 71A01 Frontiers in Microbilogy 7384750 12 https://www.frontiersin.org/journals/microbiology Frontiers 2022