
<ns0:uwmetadata xmlns:ns0="http://phaidra.univie.ac.at/XML/metadata/V1.0" xmlns:ns1="http://phaidra.univie.ac.at/XML/metadata/lom/V1.0" xmlns:ns10="http://phaidra.univie.ac.at/XML/metadata/provenience/V1.0" xmlns:ns11="http://phaidra.univie.ac.at/XML/metadata/provenience/V1.0/entity" xmlns:ns12="http://phaidra.univie.ac.at/XML/metadata/digitalbook/V1.0" xmlns:ns13="http://phaidra.univie.ac.at/XML/metadata/etheses/V1.0" xmlns:ns2="http://phaidra.univie.ac.at/XML/metadata/extended/V1.0" xmlns:ns3="http://phaidra.univie.ac.at/XML/metadata/lom/V1.0/entity" xmlns:ns4="http://phaidra.univie.ac.at/XML/metadata/lom/V1.0/requirement" xmlns:ns5="http://phaidra.univie.ac.at/XML/metadata/lom/V1.0/educational" xmlns:ns6="http://phaidra.univie.ac.at/XML/metadata/lom/V1.0/annotation" xmlns:ns7="http://phaidra.univie.ac.at/XML/metadata/lom/V1.0/classification" xmlns:ns8="http://phaidra.univie.ac.at/XML/metadata/lom/V1.0/organization" xmlns:ns9="http://phaidra.univie.ac.at/XML/metadata/histkult/V1.0">
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    <ns1:title language="en">Efﬁcacy of a modiﬁed clinoptilolite based adsorbent in reducing detrimental effects of ochratoxin a in laying hens</ns1:title>
    <ns1:language>en</ns1:language>
    <ns1:description language="en">The objective of this study was to evaluate the efﬁcacy of modiﬁed clinoptilolite
(Minazel Plus ® , MZ) as a mycotoxin adsorbent for preventing the negative the effects of ochratoxin A (OTA) on performance, pathohistological changes, and OTA residue in the eggs of laying hens. Methods: Forty eight (n = 48) laying hens (27 weeks old) were equally divided into six groups and depending on the type of addition were allocated to the following experimental treatments
for 7 weeks: E-I group-1 mg/kg OTA; E-II group 0.25 mg/kg OTA; E-III group 1 mg/kg OTA
+ 0.2% of MZ; E-IV group 0.25 mg/kg OTA + 0.2% of MZ; MZ group supplemented with 0.2% of the adsorbent; and control (K, without feed additive). Results: Overall, the addition of 0.2% MZ to laying
hen feed mitigated the harmful effects of OTA on target organs and reduced the presence of OTA residue in eggs. The groups that received 0.2% of MZ achieved better production results in terms of body weight, number of eggs, and feed consumption, compared to the other treatments. Conclusions:
The current ﬁndings conﬁrm the efﬁcacy of MZ in preventing performance losses in laying hens exposed to OTA, as well as for improving the welfare and health of food producing animals.</ns1:description>
    <ns1:keyword language="en">adsorbent; OTA; performance traits; pathohistological changes; OTA residue; eggs; risk assessment</ns1:keyword>
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      <ns2:identifier>10.3390/toxins13070469</ns2:identifier>
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        <ns3:firstname>Marko</ns3:firstname>
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        <ns3:firstname>Darko</ns3:firstname>
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        <ns3:institution>Department of Pathology, Faculty of Veterinary Medicine, University of Belgrade</ns3:institution>
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        <ns3:firstname>Dragan R.</ns3:firstname>
        <ns3:lastname>Milićević</ns3:lastname>
        <ns3:institution>Institute of meat hygiene and technology</ns3:institution>
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        <ns3:firstname>Srđan</ns3:firstname>
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        <ns3:firstname>Srđa</ns3:firstname>
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        <ns3:institution>Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine</ns3:institution>
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        <ns3:firstname>Branko</ns3:firstname>
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        <ns3:title1>Efﬁcacy of a modiﬁed clinoptilolite based adsorbent in reducing detrimental effects of ochratoxin a in laying hens</ns3:title1>
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        <ns3:firstname>Jelena</ns3:firstname>
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    <ns12:name_magazine language="en">Toxins</ns12:name_magazine>
    <ns12:pagination>469</ns12:pagination>
    <ns12:volume>13</ns12:volume>
    <ns12:publisher>MDPI</ns12:publisher>
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